“Actividad antifúngica de alpinia zerumbet frente a mohos y levaduras de importancia clínica”
Fecha
2020Autor
Cruz Alemán, Lady Stephanie
Benavides Gálvez, Laura Isabel
Metadatos
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Invasive fungal diseases (EFI) diseases to susceptible hosts, cause high impact morbidity and mortality, associated
with the high resistance to antimycotics of the agents etiological associated with this pathology. The antifungal
activity of extracts of Alpinia zerumbet, vs. C. albicans, C. parapsilosis, C. krusei, Aspergillus fumigatus, A. terreus
and Fusarium oxysporum was determined. The minimum inhibitory concentration (MIC) method and minimum
inhibitory fungal concentration (CFI) based on NTC 2455 was used. As control sample, Fluconazole standard is
considered and 96% Ethanol as a control. The alcoholic and hydroalcoholic extracts of the leaves and flowers
affected good fungistatic and fungicidal activity when compared to the control and standard sample. It is concluded
that the leaves compounds and flowers of A. zerumbet are promising for future research looking for compounds
with antimicrobial activity for use in agriculture, food, and treatment of systemic mycosis.