Now showing items 1-2 of 2
Search of allosteric inhibitors and associated proteins of an AKT-like kinase from trypanosoma cruzi
(MDPI AG, 2018-12-12)
Proteins associated to the PI3K/AKT/mTOR signaling pathway are widely used targets for cancer treatment, and in recent years they have also been evaluated as putative targets in trypanosomatids parasites, such as Trypanosoma ...
The Akt-like kinase of Leishmania panamensis: As a new molecular target for drug discovery
(Elsevier B.V., 2018-01-01)
The Akt-like kinase of Leishmania spp. is a cytoplasmic orthologous protein of the serine/threonine kinase B-PKB/human-Akt group, which is involved in the cellular survival of these parasites. By the application of a ...