Now showing items 1-2 of 2
Identification of a RAC/AKT-like gene in Leishmania parasites as a putative therapeutic target in leishmaniasis
(BioMed Central Ltd., 2017-10-10)
Background: Leishmaniasis is one of the world's most neglected diseases caused by at least 20 different species of the protozoan parasite Leishmania. Although new drugs have become recently available, current therapy for ...
Development of a novel formulation with hypericin to treat cutaneous leishmaniasis based on photodynamic therapy in in vitro and in vivo studies
(Universidad Santiago de Cali, 2015-09-01)
An evaluation of the leishmanicidal activity in vitro and in vivo of hypericin, an expanded-spectrum photosensitizer found in Hypericum perforatum, is presented. Hypericin was evaluated against intracellular amastigotes ...