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Identification of a RAC/AKT-like gene in Leishmania parasites as a putative therapeutic target in leishmaniasis 

Varela-M, R. E.; Ochoa, Rodrigo; Muskus, Carlos Enrique; Muro, Antonio; Mollinedo, Faustino (BioMed Central Ltd., 2017-10-10)
Background: Leishmaniasis is one of the world's most neglected diseases caused by at least 20 different species of the protozoan parasite Leishmania. Although new drugs have become recently available, current therapy for ...
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The Akt-like kinase of Leishmania panamensis: As a new molecular target for drug discovery 

Tirado-Duarte, Didier; Marín-Villa, Marcel; Ochoa, Rodrigo; Blandón-Fuentes, Gustavo; Soares, Maurílio José; Robledo, Sara María; Varela-M, R. E. (Elsevier B.V., 2018-01-01)
The Akt-like kinase of Leishmania spp. is a cytoplasmic orthologous protein of the serine/threonine kinase B-PKB/human-Akt group, which is involved in the cellular survival of these parasites. By the application of a ...

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AuthorOchoa, Rodrigo (2)
Varela-M, R. E. (2)
Blandón-Fuentes, Gustavo (1)Marín-Villa, Marcel (1)Mollinedo, Faustino (1)Muro, Antonio (1)Muskus, Carlos Enrique (1)Robledo, Sara María (1)Soares, Maurílio José (1)Tirado-Duarte, Didier (1)SubjectAnimals (2)
Humans (2)
Macrophages (2)Nonhuman (2)Akt protein (1)amphotericin B (1)Antibodies, Protozoan (1)Apoptosis (1)Cell survival (1)Chemistry (1)... View MoreDate Issued2017 (1)2018 (1)Has File(s)Yes (2)

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