Now showing items 1-2 of 2
Search of allosteric inhibitors and associated proteins of an AKT-like kinase from trypanosoma cruzi
(MDPI AG, 2018-12-12)
Proteins associated to the PI3K/AKT/mTOR signaling pathway are widely used targets for cancer treatment, and in recent years they have also been evaluated as putative targets in trypanosomatids parasites, such as Trypanosoma ...
Identification of a RAC/AKT-like gene in Leishmania parasites as a putative therapeutic target in leishmaniasis
(BioMed Central Ltd., 2017-10-10)
Background: Leishmaniasis is one of the world's most neglected diseases caused by at least 20 different species of the protozoan parasite Leishmania. Although new drugs have become recently available, current therapy for ...