Now showing items 1-10 of 11
Should we nebulize hypertonic saline prophylactically in our pediatric intubated patients?
(American Association for Respiratory Care, 2016-05-01)
Reliability and dimensionality of PHQ-9 in screening depression symptoms among health science students in Cartagena, 2014
(Instituto Nacional de Salud, 2017-04-01)
Introduction: Depression among university students must be screened with valid instruments. The Patient Health Questionnaire (PHQ-9) is reliable and valid for screening depression in a university context; however, its ...
Identification of a RAC/AKT-like gene in Leishmania parasites as a putative therapeutic target in leishmaniasis
(BioMed Central Ltd., 2017-10-10)
Background: Leishmaniasis is one of the world's most neglected diseases caused by at least 20 different species of the protozoan parasite Leishmania. Although new drugs have become recently available, current therapy for ...
Emerging trends in invasive and noninvasive isolates of Streptococcus agalactiae in a Latin American hospital: A 17-year study
(BioMed Central Ltd., 2014-08-03)
Background: Streptococcus agalactiae or group B Streptococcus (GBS) has been recognized as a lethal pathogen in neonates worldwide. S. agalactiae infections also severely affect pregnant women and immunosuppressed adults ...
Antitumor activity of artemisinin and its derivatives: From a well-known antimalarial agent to a potential anticancer drug
Improvement of quality of life and survival of cancer patients will be greatly enhanced by the development of highly effective drugs to selectively kill malignant cells. Artemisinin and its analogs are naturally occurring ...
Development of a novel formulation with hypericin to treat cutaneous leishmaniasis based on photodynamic therapy in in vitro and in vivo studies
(Universidad Santiago de Cali, 2015-09-01)
An evaluation of the leishmanicidal activity in vitro and in vivo of hypericin, an expanded-spectrum photosensitizer found in Hypericum perforatum, is presented. Hypericin was evaluated against intracellular amastigotes ...
(Sociedad Chilena de Infectologia, 2016-08-06)
Strongyloidiasis is an infection caused by the parasite Strongyloides stercoralis, which can be asymptomatic and means a high morbidity and mortality in immunocompromised hosts, severe malnutrition and coinfection with ...
Haemoglobin degradation underpins the sensitivity of early ring stage Plasmodium falciparum to artemisinins
(Company of Biologists Ltd, 2016-01-01)
Current first-line artemisinin antimalarials are threatened by the emergence of resistant Plasmodium falciparum. Decreased sensitivity is evident in the initial (early ring) stage of intraerythrocytic development, meaning ...
Metodología para la elaboración de canales endémicos y tendencia de la notificación del dengue, Valle del Cauca, Colombia, 2009-2013
(Instituto Nacional de Salud, 2016-01-01)
Introduction: Dengue is the fastest spreading disease in the world and a permanent threat to global public health. It is a viral illness for which approximately 2.5 million people are at high risk of infection. Given the ...
The Akt-like kinase of Leishmania panamensis: As a new molecular target for drug discovery
(Elsevier B.V., 2018-01-01)
The Akt-like kinase of Leishmania spp. is a cytoplasmic orthologous protein of the serine/threonine kinase B-PKB/human-Akt group, which is involved in the cellular survival of these parasites. By the application of a ...