Mostrando ítems 1-5 de 5
Identification of a RAC/AKT-like gene in Leishmania parasites as a putative therapeutic target in leishmaniasis.
(Parasites and Vectors, 2018)
Background Leishmaniasis is one of the world’s most neglected diseases caused by at least 20 different species of the protozoan parasite Leishmania. Although new drugs have become recently available, current therapy for ...
C-Geranylated flavonoids from Paulownia tomentosa fruits with antimicrobial potential and synergistic activity with antibiotics
(Pharmaceutical Biology, 2016)
Context C-6-Geranylated flavonoids possess promising biological activities. These substances could be a source of lead compounds for the development of therapeutics.Objective The study was designed to evaluate their ...
Identificación molecular de aislamientos clínicos de Leishmania spp. procedentes de Colombia con base en el gen hsp70
(Biomedica : revista del Instituto Nacional de Salud, 2016)
La leishmaniasis es una enfermedad de gran prevalencia en Colombia, donde al menos seis especies diferentes la originan en el ser humano, con un amplio rango de características clínicas. La tipificación de la especie es ...
Identification of a RAC/AKT-like gene in Leishmania parasites as a putative therapeutic target in leishmaniasis
(BioMed Central Ltd., 2017-10-10)
Background: Leishmaniasis is one of the world's most neglected diseases caused by at least 20 different species of the protozoan parasite Leishmania. Although new drugs have become recently available, current therapy for ...
Development of a novel formulation with hypericin to treat cutaneous leishmaniasis based on photodynamic therapy in in vitro and in vivo studies
(Universidad Santiago de Cali, 2015-09-01)
An evaluation of the leishmanicidal activity in vitro and in vivo of hypericin, an expanded-spectrum photosensitizer found in Hypericum perforatum, is presented. Hypericin was evaluated against intracellular amastigotes ...